Neonatal circumcision in severe haemophilia: a survey of paediatric haematologists at United States Hemophilia Treatment Centers

• DOI: 10.1111/hae.12528
• Publication Date: 2014-12-05T12:22:36Z
• Authors: S. Kearney; A. Sharathkumar; V. Rodriguez; M. Chitlur; L. Valentino; L. Boggio; J. Gill
• Keywords: Haemophilia B

Neonatal circumcision in patients with severe haemophilia has not been well studied. We performed a survey of paediatric haematologists from Hemophilia Treatment Centers (HTC) across the United States to better understand attitudes toward and management neonatal patients. Response rate our was 40% (n = 64/159). Thirty-eight percent respondents 24) said that they would allow this procedure newborn period but many cases against medical advice. The most reported concern regarding risk development an inhibitor 25; 39%) followed by for bleeding 22; 34%) issues related vascular access neonate 11; 17%). All recommended at least one preprocedure dose factor replacement. Twenty-two 14) did use more than replacement 32% 21) used 1-2 postoperative doses. remainder surveyed between 3-5 (16%; n 10) 6-10 (3%, 2) additional days postoperatively. There wide variation both techniques as adjuvant haemostatic agents used. Only 22% had established protocol patient. These results highlight need evidence-based guidelines optimal neonates haemophilia.