Surgical Resection in the Management of Pulmonary Metastatic Disease of Gestational Trophoblastic Neoplasia

• DOI: 10.1111/igc.0b013e3181a3d014
• Publication Date: 2010-12-03T18:53:16Z
• Authors: Y.a.n.g. Cao; Y.a.n.g. Xiang; Fengzhi Feng; Xirun Wan; Xiuyu Yang
• Keywords: Medical record; Gestational trophoblastic neoplasia; Group B

The objective of this study was to evaluate the influence surgical resection on survival outcome in patients with gestational trophoblastic neoplasia pulmonary metastatic disease. Medical records 62 who underwent lobectomy or limited were reviewed. cases divided into 3 groups, namely, recurrent group (group A), drug-resistant B), and satisfactory response chemotherapy but residual lesion C). proportion high-risk significantly lower C, whereas had a remarkable complete remission rate 100% no relapse recorded, only (12.0%) positive histologic diagnosis. rates groups A B 88.9% 78.6%, respectively, 14.3% 15.0%, respectively. By comparing treatment failure achieved remission, factors that might affect clinical surgery also analyzed. Patients have received more than 4 regimens 13 courses preoperative seemed unfavorable prognosis (P < 0.05). Follow-ups could be carried out without for lesions. Pulmonary is indicated when evidence suggests disease causes drug-resistance lesions are relatively localized. However, not advisable chemotherapy.