Chronic generalized pruritus without primary skin lesions: a longitudinal prospective observational study

• DOI: 10.1111/ijd.14125
• Publication Date: 2018-07-24T17:58:20Z
• Authors: Narges Alizadeh; Seyyed Hossein Mi...; Razieh Golmohamadi; Abbas Darjani; Hojat Eftekhari; Rana Rafiei; Kaveh Gharaei Nejad; Seyyede Zeinab Azimi
• Keywords: Adult; Aged, 80 and over; Male; Pruritus; Middle Aged; Thyroid Diseases; 3. Good health; Diabetes Complications; 03 medical and health sciences; Sex Factors; 0302 clinical medicine; Neoplasms; Chronic Disease; Humans; Female; Longitudinal Studies; Prospective Studies; Age of Onset; Aged

Pruritus is among the most common complaints in field of dermatology. It also a disturbing symptom many systemic disorders. Chronic pruritus (CP) refers to cases which last longer than 6 weeks. We conducted prospective analysis patients with generalized without primary skin lesions. All underwent evaluations and then were followed from 12 18 months for further evaluations. Of 5,127 referred our dermatology clinic, 49 lesions evaluated. Most (44%) age group 40–60 years female (58%). The duration was 37.04 ± 30.4 Fifty percent had cause pruritus. underlying diseases thyroid disorders (16.67%), diabetes mellitus (12.5%), malignancy (8.33%). There no significant statistical differences terms their age, gender, disease (P = 0.47, P 0.99, 0.816, respectively). However, average onset earlier women regardless 0.011). Based on findings study, we recommend considering endocrine malignancies as leading chronic