Risk stratification of adolescents for the screening of non‐alcoholic fatty liver disease

• DOI: 10.1111/ijpo.12924
• Publication Date: 2022-05-03T02:10:00Z
• Authors: Gary A. Abrams; Deanna Ware; Margaret M. Byrne; Eric M. Hecht
• Keywords: Transient elastography; Alcoholic fatty liver

Non-alcoholic fatty liver conditions in adolescence are associated with premature mortality adulthood. Effective screening could impact the population burden of this disease.We sought to determine which adolescents should be screened for non-alcoholic using vibration-controlled transient elastography.We simulated a program 938 from National Health and Nutritional Examination Survey 2017/2018. We stratified subjects by body mass index metabolic parameters analyzed our data standard diagnostic statistical measures.The weighted prevalence disease was 24.4%, 3.8%, respectively. For all obesity (21.8% population), identified 61.8% cases. In category overweight abnormalities (26.7% 71.2% cases.The two groups most likely benefit elastography one abnormality. These criteria reduce number individuals tested approximately 80% (from an approximate 32 million 6-7.5 adolescents), while retaining accuracy 84%-85%.