Human bocavirus and human metapneumovirus in hospitalized children with lower respiratory tract illness in Changsha, China

• DOI: 10.1111/irv.12535
• Publication Date: 2017-12-23T13:45:27Z
• Authors: Jie‐ying Zhou; Ying Peng; Xiao‐you Peng; Han‐chun Gao; Ya‐ping Sun; Le‐yun Xie; Li‐li Zhong; Zhao‐jun Duan; Zhi‐ping Xie; You‐de Cao
• Keywords: Human bocavirus; Metapneumovirus; Respiratory illness; Respiratory tract

Lower respiratory tract illness is a major cause of morbidity and mortality in children worldwide, however, information about the epidemiological clinical characteristics LRTIs caused by HMPV HBoV China limited.Human bocavirus (HBoV) human metapneumovirus (HMPV) are two important viruses for with lower infections (LRTI). We aimed to assay correlation between viral load LRTI Changsha, China.Nasopharyngeal aspirates (NPAs) from were collected. Real-time PCR was used screen HMPV. Analyses performed using SPSS 16.0 software.Pneumonia most frequent diagnosis. There no significant difference HBoV- HMPV-positive patients age (P = .506) or hospitalization duration .280); 24.1% 18.2% positive peaked summer (32.2%), winter (28.9%). The HBoV-positive had shorter than HBoV-negative .021), higher prevalence fever HMPV-negative .002). significantly among aged <1 year .006). mean loads not different single coinfections. Patients infected only older those coinfected other .005). No found viruses.Pneumonia diagnosis Neither nor correlated disease severity.