Disruption of barrier function in dermatophytosis and pityriasis versicolor

• DOI: 10.1111/j.1346-8138.2011.01320.x
• Publication Date: 2011-09-27T13:50:56Z
• Authors: Weon Ju LEE; Jun Young KIM; Chang Hyun SONG; Hong Dae JUNG; Seok‐Jong LEE; Do Won KIM
• Keywords: Pityriasis; Skin Barrier

Dermatophytes have the ability to form molecular attachments keratin and use it as a source of nutrients, colonizing keratinized tissues, including stratum corneum skin. Malassezia species also affect Therefore, dermatophytosis pityriasis versicolor skin are thought be important factors profound changes in barrier structure function. We aimed describe transepidermal water loss (TEWL), hydration, pH lesions versicolor. Thirty-six patients with (14 tinea cruris, 13 corporis nine pedis or manus) 11 were included this study. TEWL, conductance determined by biophysical methods examine whether our exhibited Dermatophytosis except manus showed highly significant increase TEWL compared adjacent infection-free Hydration was significantly reduced lesional From study, infections dermatophytes on body can alter properties skin, especially function loss. On contrary, palms soles little