Immunogenetic studies of juvenile dermatomyositis

• DOI: 10.1111/j.1399-0039.1983.tb00371.x
• Publication Date: 2010-07-23T23:40:38Z
• Authors: J. M. Friedman; L. M. Pachman; M. L. Maryjowski; O. Jonasson; N. D. Battles; W. E. Crowe; C. W. Fink; V. Hanson; J. E. Levinson; C. H. Spencer; D. B. Sullivan
• Keywords: Juvenile Dermatomyositis; Proband; Abnormality

Typing for HLA‐A and ‐B antigens was performed on 87 children with definite juvenile dermatomyositis (JDMS). A significantly increased frequency of HLA‐B8 (estimated relative risk = 2.8, P c < 0.01) observed among White patients, but not Blacks or Latin Americans JDMS. No abnormality HLA haplotype segregation 38 healthy siblings the JDMS probands.