Molecular Genetic Analysis of the ABO Blood Group System: 2. cis‐AB Alleles

• DOI: 10.1111/j.1423-0410.1993.tb02529.x
• Publication Date: 2009-03-05T20:39:54Z
• Authors: Fumi‐ichiro Yamamoto; Patricia D. McNeill; Yoshihiko Kominato; Miyako Yamamoto; Sen‐itiroh Hakomori; Seiji Ishimoto; Sachiyo Nishida; Masayuki Shima; Yoshihiro Fujimura
• Keywords: Amino acid substitution; Coding region

Abstract We have determined the nucleotide sequence of coding region in last two exons ABO genes from cis ‐AB individuals (genotype ‐AB/O) with no consanguinity. In this region, alleles these 2 were identical to one another while different A 1 allele by substitutions. Both substitutions result amino acid The first substitution is previously found allele. other at fourth position four which discriminate and B transferases.