Prospective evaluation of the optimal number of 25‐gauge needle passes for endoscopic ultrasound‐guided fine‐needle aspiration biopsy of solid pancreatic lesions in the absence of an onsite cytopathologist

• DOI: 10.1111/j.1443-1661.2012.01311.x
• Publication Date: 2012-04-10T07:28:19Z
• Authors: Rei Suzuki; Atsushi Irisawa; Manoop S. Bhutani; Takuto Hikichi; Tadayuki Takagi; Ai Sato; Masaki Sato; Tsunehiko Ikeda; Ko Watanabe; Jun Nakamura; Kazuhiro Tasaki; Katsutoshi Obara; Hiromasa Ohira
• Keywords: Cytopathology; Endoscopic Ultrasound; Needle biopsy; Fine needle biopsy

Introduction: A prior study with 22‐gauge needles recommended more than seven needle passes for endoscopic ultrasound‐guided fine‐needle aspiration biopsy (EUS‐FNA) of solid pancreatic lesions (SPL) without onsite cytopathology optimal acquisition cytopathological diagnosis. The feasibility this recommendation should be re‐evaluated considering the later development and popularity 25‐gauge EUS‐FNA needles. We aimed to determine number specimen SPL. Methods: preliminary prospective 22 patients an technician showed a sensitivity 93.3% specificity 100% four that was not statistically different from five passes. Based on our study, we fixed (Group A). As control group, carried out sampling in consecutive using cytopathologist B). Sampling rate, diagnostic value complications were evaluated. Results: enrolled 20 each group. rate higher Group B (20/20, 100%) (19/20, 95%), but there no statistical difference between them ( P ‐value = 0.31). In A, sensitivity, accuracy among 19. B, 94.1%, 100%, 95%. There also differences groups. No seen. Conclusion: Our suggests may sufficient SPL where cytology is available.