Is there a role for in vivo methylene blue staining in the prediction of bladder tumour recurrence?

• DOI: 10.1111/j.1464-410x.1995.tb07268.x
• Publication Date: 2008-11-21T17:13:36Z
• Authors: T.A. Creagh; M. Gleeson; D. Travis; R. Grainger; T.E.D. McDermott; M.R. Butler
• Keywords: Methylene blue; Carcinoma in situ; Needle biopsy

To assess the role of in vivo staining with intravesical methylene blue predicting tumour recurrence.Thirty-nine patients (27 men and 12 women, age range 43-75 years) newly diagnosed bladder tumours were prospectively studied followed for a minimum 2 years. Potential biopsy sites identified by intravesically 1% solution compared random sites.Biopsy directed detected carcinoma situ more often than biopsy. Rates recurrence similar both stained unstained groups.Methylene does not add significantly to management presenting tumours.