Multilocular cystic renal cell carcinoma: clinicopathological features and preoperative prediction using multiphase computed tomography

• DOI: 10.1111/j.1464-410x.2011.10247.x
• Publication Date: 2011-07-01T13:39:24Z
• Authors: Dalsan You; Myungsun Shim; In Gab Jeong; Cheryn Song; Jeong Kon Kim; Jae Y. Ro; Jun Hyuk Hong; Hanjong Ahn; Choung‐Soo Kim
• Keywords: Hounsfield scale

Study Type – Diagnostic (exploratory cohort) Level of Evidence 2b What’s known on the subject? and What does study add? Multilocular cystic renal cell carcinoma (MCRCC), defined according to 2004 WHO classification, has good prognosis, which is not affected adversely by large tumour size or advanced stage. Thus nephron‐sparing surgery proposed when MCRCC suspected preoperative radiologic criteria. The present confirms low malignant potential MCRCC. Additionally, results provide a simple, useful criteria using Bosniak classification Hounsfield unit multiphase computed tomography images differentiate from other RCC. OBJECTIVE • To analyse clinicopathological radiological features multilocular (MCRCC) determine factors differentiating RCC (CRCC). PATIENTS AND METHODS medical records 53 patients with complex masses evaluated (CT), surgically removed confirmed as sporadic were reviewed. Of these patients, 23 classified having 30 CRCCs, RCCs extensive change necrosis. Another 22 treated for presumed be diagnosed benign cyst. RESULTS Benign cysts MCRCCs significantly more likely III than CRCCs (77% vs 61% 27%, P = 0.001). mean (HU) during corticomedullary phase (CMP) was higher in HU ≥38 83% sensitivity 80% specificity predicting CRCCs. In multiple regression model, CMP independent predictive 41 >4 cm diameter, combination IV showed 63% sensitivity, 96% specificity, 91% positive value negative value, yielding 2% false‐positive 15% false‐negative rates. CONCLUSIONS can This could help selecting an appropriate surgical method, such surgery, cm.