Serum lipids in early pregnancy and risk of pre‐eclampsia

• DOI: 10.1111/j.1471-0528.1996.tb09661.x
• Publication Date: 2005-08-19T09:52:08Z
• Authors: Helga J. van den ...; Juriy W. Wladimiroff; Titia E. Cohen‐Ov...; Anton J. de Bruijn; Diederick E. Grobbee
• Keywords: High-density lipoprotein

To determine whether first and late second trimester serum total high density lipoprotein cholesterol are associated with blood pressure, uterine artery pulsatility index pregnancy outcome.A prospective cohort study. Data were analysed using multiple linear logistic regression analysis.Three hundred ninety-three pregnant women requesting chorionic villus sampling because of advanced maternal age (36 years older).Serum measured by an automated enzymatic method. Uterine flow velocity waveforms recorded continuous Doppler ultrasound. Pregnancy outcome was assessed questionnaire.First significantly the risk pre-eclampsia, adjusted relative exceeding 5 for levels above 6.0 mmol/1 when compared a level below 5.0 mmol/1. First also showed significant relationship diastolic pressure (coefficient = 0.02 (mmol/1)/mm Hg, 95% CI 0.01 to 0.03), change in both systolic from changes cholesterol.These data suggest relation between lipids early development pre-eclampsia.