Cardiac Sarcoidosis: Electrophysiological Outcomes on Long‐Term Follow‐Up and the Role of the Implantable Cardioverter‐Defibrillator

• DOI: 10.1111/jce.12302
• Publication Date: 2013-10-30T15:42:55Z
• Authors: AMR MOHSEN; ALEJANDRO JIMENEZ; ROBERT E. HOOD; TIMM DICKFELD; ANASTASIOS SALIARIS; STEPHEN SHOROFSKY; MAGDI M. SABA
• Keywords: Electrophysiology study

Cardiac Sarcoidosis Objectives The objectives of this study were to identify the predictors life‐threatening ventricular arrhythmias in patients with cardiac sarcoidosis (CS) and evaluate role implantable cardioverter‐defibrillator (ICD) patient population. Background ICD implantation is a class IIA recommendation for CS. However, some indications CS are still unclear not enough data available establish malignant tachyarrhythmias group patients. Methods We retrospectively identified all consecutive who diagnosed CS, during period from March 2002 April 2010. rhythm devices regularly interrogated clinical recorded follow‐up visits. Results Thirty‐three (17 male) identified. mean age was 53 ± 11. left ejection fraction (LVEF) 41 18%. Thirty received an ICD. Twelve (36.3%) had sustained arrhythmias. Eleven appropriate therapies 9 inappropriate shocks, representing 36.7% 30.0% population, respectively. Patients younger 47.4 7.8, lower LVEF 33.0 12.0 compared those did receive (P = 0.0301 0.0341, respectively). There no other demographic, clinical, electrocardiographic, electrophysiological, or imaging markers that predicted future occurrence our cohort Conclusions strongly associated No specific such emerged, than young low LVEF.