Cervical cytological abnormalities and human papilloma virus infection in women infected with HIV in Southern India

• DOI: 10.1111/jog.13111
• Publication Date: 2016-09-19T12:17:07Z
• Authors: Suchitra Thunga; Anusmitha Andrews; John Ramapuram; Kapaettu Satyamoo...; Hema Kini; B. Unnikrishnan; Prabha Adhikari; Prakhar Singh; Shama Prasada Kab...; Samatha Bhat; Anagha Kadam; Avinash K Shetty
• Keywords: Adult; Human papillomavirus 16; Genotype; Human papillomavirus 18; Papillomavirus Infections; India; HIV Infections; Uterine Cervical Dysplasia; 3. Good health; CD4 Lymphocyte Count; 03 medical and health sciences; Cross-Sectional Studies; 0302 clinical medicine; Humans; Female; Early Detection of Cancer; Papanicolaou Test

The aim of this study was to examine the association between CD4 count, human papilloma virus (HPV) infection, and risk cervical intraepithelial neoplasia among HIV-infected women.A cross-sectional conducted 104 women attending an antiretroviral therapy clinic. They underwent Pap smear HPV DNA testing.The overall prevalence infection 57.7%. 16 commonest genotype found (38.5%); 18 put together contributed 73.3% infection; 27.5% had squamous cell abnormalities. Cervical less likely with count > 500/mm3 (12%) in those without opportunistic infections (17.8%). high-risk higher high-grade lesions or greater (85.7%) as compared normal cytology (52.1%).The high warrants need for regular screening these routine vaccination adolescents reduce burden cancer India.