Retrospective study of aldosterone and progesterone secreting adrenal tumors in 10 cats

• DOI: 10.1111/jvim.16256
• Publication Date: 2021-09-02T19:20:00Z
• Authors: Cailin C. Harro; Kent R. Refsal; Nicole Shaw; Samantha M. Alston; William Folger; Carolyn Gross; W. Mark Cousins; Colleen F. Monahan; Michal Mazaki‐Tovi; Daniel K. Langlois
• Keywords: Hyperaldosteronism; Medical record

Abstract Background Primary hyperaldosteronism caused by adrenal neoplasia has been well described in cats. Multiple corticosteroid abnormalities occur a subset of affected cats, but characterizations this syndrome are limited to several case reports. Objectives To describe series cats with tumors secreting aldosterone and additional corticosteroids. Animals Ten multiple adrenocortical tumors. Methods Retrospective series. Medical records both progesterone were identified. Data concerning historical findings, clinicopathologic features, treatments, outcomes retrieved from medical records. Results All 10 had diabetes mellitus addition biochemical features such as hypokalemia. High corticosterone concentrations observed all 3 which was measured. Ultrasound examinations revealed unilateral cases, the contralateral gland either atrophied or not identified 5 Three 4 developed hypoadrenocorticism after surgical adrenalectomy. achieved diabetic remission Two treated adrenalectomy survived >1 year, 1 cat 6.5 months, alive 5.5 months diagnosis. Survival year occurred 2 management alone. treated. Conclusions Clinical Importance The presence should be considered tumors, especially those concurrent mellitus. Both can result long‐term survival, although documented only undergoing