In vitro and in vivo evaluation of Weissella cibaria and Lactobacillus plantarum for their protective effect against cadmium and lead toxicities

• DOI: 10.1111/lam.12731
• Publication Date: 2017-03-09T08:22:59Z
• Authors: O. Ojekunle; K. Banwo; A.I. Sanni
• Keywords: Weissella

Thirty-two lactic acid bacteria (LAB) isolates were obtained from fermenting cassava mash and wara (African soft cheese) screened for their resistance to cadmium lead toxicities at 550-1050 mg l-1 probiotic potentials. Four LAB strains that tolerated the heavy metals 1050 selected antioxidative capacities, tolerance acid, bile salts simulated gastric intestinal tract safety status. The results revealed Weissella cibaria WD2 Lactobacillus plantarum CaD1 exhibited comparatively higher survived in transit, salt possessed two employed vivo studies, which was monitored male albino Wistar rats using skim milk as a carrier cultures over period of 28 days. given W. L. addition with administration had improved renal hepatic impairment, while damage observed fed only. demonstrated potentials These can be used effectively amend histopathological alterations caused by ingestion lead.This present study highlights presence traditional fermented foods resistant studies ameliorated build-up organs animals. This indicated good binding prevent exposure these metals.