Progress towards hepatitis C virus elimination in high‐income countries: An updated analysis

• DOI: 10.1111/liv.14779
• Publication Date: 2021-01-03T02:35:28Z
• Authors: Ivane Gamkrelidze; Jean‐Michel Pawlo...; Jeffrey V. Lazarus; Jordan J. Feld; Stefan Zeuzem; Yanjun Bao; Ana Gabriela Pire...; Yuri Sanchez Gonz...; Homie Razavi
• Keywords: Sweden; 0301 basic medicine; Canada; Developed Countries; Australia; Iceland; Saudi Arabia; Hepacivirus; Antiviral Agents; Hepatitis C; 3. Good health; 03 medical and health sciences; Italy; Japan; Spain; Austria; Germany; Republic of Korea; Humans; France; Switzerland; Netherlands; New Zealand

ABSTRACT BACKGROUND & AIMS Elimination of HCV by 2030, as defined the World Health Organization (WHO), is attainable with availability highly efficacious therapies. This study reports progress made in timing elimination 45 high‐income countries between 2017 and 2019. METHODS Disease progression models infection for each country were updated latest data on chronic prevalence, annual diagnosis treatment levels, assumed to remain constant future. Modelled outcomes analysed determine year which would meet WHO 2030 targets. RESULTS Of studied, 11 (Australia, Canada, France, Germany, Iceland, Italy, Japan, Spain, Sweden, Switzerland, United Kingdom) are track WHO's targets 2030; five (Austria, Malta, Netherlands, New Zealand, South Korea) 2040; two (Saudi Arabia Taiwan) 2050. The remaining 27 not expected achieve before Compared 2017, Korea no longer eliminate three (Canada, Sweden) now track, most (30) saw change. CONCLUSIONS Assuming will maintain current levels treatment, only 24% 60% off at least 20 years. If continue falling, achieving be more challenging. With less than ten years remaining, screening expansion crucial