Angioedema without urticaria in childhood

• DOI: 10.1111/pai.12118
• Publication Date: 2013-09-13T02:39:49Z
• Authors: Hacer I. Ertoy Ka...; Ozlem Yilmaz; Arzu Bakirtas; Erdem Topal; Mehmet S. Demirsoy; Ipek Turktas
• Keywords: Male; Adolescent; Urticaria; Histamine Antagonists; Thyroiditis, Autoimmune; Infant; Infections; Prognosis; 3. Good health; 03 medical and health sciences; 0302 clinical medicine; Recurrence; Child, Preschool; Hypersensitivity; Humans; Female; Prospective Studies; Angioedema; Child; Algorithms; Follow-Up Studies

Abstract Background There has been no separate study investigating angioedema without urticaria ( A w/o U ) exclusively in children so far. The purpose of this was to investigate the frequency, clinical presentation, etiology, management and follow‐up children. Methods This is a prospective that included all consecutive patients with history referred our clinic between January 2011 May 2012. standard diagnostic therapeutic algorithm applied patients. Results frequency found be 1.6% during period. An etiological factor could only 45 (49%). causes were infection (21%), allergy (14%), thyroid autoimmunity TA )‐related (8%) nonsteroid anti‐inflammatory drug hypersensitivity (6%), idiopathic (51%). hereditary type I, II or acquired rare syndromes associated . median 16 months (range: 12–30 months). Antihistamine prophylaxis initiated at doses 20 frequently recurrent due euthyroid ‐related for 3 months. These responded antihistamine Four relapsed after cessation end prolonged 6 three 9 one patient. Conclusions Angioedema condition etiology can identified half them. treatment alone sufficient, prognosis good non cases short‐term