AtCAF‐1 mutants show different DNA damage responses after ultraviolet‐B than those activated by other genotoxic agents in leaves

• DOI: 10.1111/pce.13596
• Publication Date: 2019-05-30T19:09:18Z
• Authors: Evangelina Maulión; María Sol Gomez; Claudia Anabel Bu...; Paula Casati
• Keywords: Pyrimidine dimer; Elongation

Chromatin assembly factor-1 (CAF-1) is a histone H3/H4 chaperone that participates in DNA and chromatin interaction processes. In this manuscript, we show organs from CAF-1 deficient plants respond differently to ultraviolet-B (UV-B) radiation than other genotoxic stresses. For example, leaves tolerate better UV-B radiation, showing lower cyclobutane pyrimidine dimer (CPD) accumulation, inhibition of cell proliferation, increased wall thickness, absorbing compounds, ploidy levels, whereas previous data different groups have shown mutants shortening telomeres, loss 45S rDNA, homologous recombination, phenotypes associated breaks. Interestingly, roots primary root elongation, with decreased meristem size due higher proliferation after exposure. The decrease consequence defects programmed death Together, provide evidence demonstrating shoot meristematic cells may distinct protection mechanisms against CPD accumulation by UV-B, which be linked functions the complex these organs.