The rice heavy‐metal transporter OsNRAMP1 regulates disease resistance by modulating ROS homoeostasis

• DOI: 10.1111/pce.14263
• Publication Date: 2022-01-18T07:21:46Z
• Authors: Chuanliang Chu; Renyan Huang; Liping Liu; Guilin Tang; Jinghua Xiao; Heejin Yoo; Meng Yuan
• Keywords: Homeostasis

Abstract Crop diseases threaten food security and sustainable agriculture. Consumption of crops containing nonessential toxic metals leads to health risks for humans. Therefore, cultivation disease‐resistant metal‐safe is a double‐gain strategy that can contribute security. Here, we show rice heavy‐metal transporter OsNRAMP1 plays an important role in plant immunity by modulating metal ion reactive oxygen species (ROS) homoeostasis. expression was induced after pathogenic bacteria fungi infections. The osnramp1 mutants had increased content H 2 O activity superoxide dismutase, but decreased catalase, showing enhanced broad‐spectrum resistance against bacterial fungal pathogens. RNA‐seq analysis identified number differentially expressed genes were involved ROS Altered ion‐dependent ROS‐scavenging enzymes lower accumulation cations such as Mn together compromised enzyme‐catalysing modulated homoeostasis, which contributed towards disease mutants. Furthermore, the contained levels heavy Cd Pb micronutrients Ni leaves grains. Taken together, proof concept achieved heavy‐metal‐safe engineered removal gene.