Waiting list mortality for pediatric deceased donor liver transplantation in a Japanese living‐donor–dominant program

• DOI: 10.1111/petr.13578
• Publication Date: 2019-09-19T10:30:46Z
• Authors: Mureo Kasahara; Masami Katono; Andrea Schlegel; Tomomi Kubota; Yayoi Nakazato; Hajime Uchida; Seiichi Shimizu; Yusuke Yanagi; Masahiro Takeda; Akinari Fukuda; Seisuke Sakamoto
• Keywords: Liver disease; Waiting list

Abstract Living donor liver transplantation (LDLT) has become a major life‐saving procedure for children with end‐stage disease in Japan, whereas deceased (DDLT) achieved only limited success. The annual number of pediatric transplantations is approximately 100‐120, patient 20‐year survival rate 81.0%. In 2005, the program at National Center Child Health and Development Tokyo, was initiated, an overall 560 patients to date. July 2010, our center qualified as DDLT center; total 132 were listed up until February 2019. indications included acute failure (n = 46, 34.8%), metabolic 26, 19.7%), graft after LDLT 17, 12.9%), biliary atresia 16, 12.1%), primary sclerosing cholangitis 10, 7.6%). Overall, 25.8% on waiting list received 52.3% transplanted from living donor. 5‐year survivals 90.5% 88.8%, respectively, mortality 3.0%. provides better compared among recipients list. nevertheless great importance Japan; however, it cannot save all recipients. As not yet been reduced zero, both should be implemented programs.