Primary pulmonary angiosarcoma: A case report

• DOI: 10.1111/pin.12341
• Publication Date: 2015-08-14T06:25:46Z
• Authors: Hiroyuki Tanaka; Kenji Yorita; Nobuyasu Takahashi; Yasuhiro Usuma; Kunihide Nakamura; Hiroaki Kataoka
• Keywords: CD31

Primary sarcoma is uncommon in the lung, and primary angiosarcoma exceedingly rare. We report a case of pulmonary left lung with emphasis on its growth pattern lung. A 48‐year‐old Japanese man was admitted to our hospital because dyspnea exertion. He subsequently found have pleural effusion. Computed tomography shows nodular lesion measuring 7 × 4 cm his Obstruction inferior lobar bronchus observed, endobronchial biopsy suggested angiosarcoma. Left pneumonectomy performed. On macroscopic examination cut surface, multiple lesions were observed particularly portions around branches artery along bronchioles. Histological revealed vascular channel‐like structure vague lumen formations by atypical polygonal or spindle‐shaped neoplastic cells. Immunohistochemically, cells are positive for FLI ‐1, ERG , CD31 von Willebrand factor/factor VIII ‐related antigen, but not CD34 . Angiosarcoma rare form tumors, this describes unique