Antioxidant response element activator, BTZO‐1, improves the developmental competence of bovine oocytes

• DOI: 10.1111/rda.13733
• Publication Date: 2020-05-30T21:56:55Z
• Authors: Mansour Aboelenain; Wael B. El_domany; Haitham Eldoumani; Wael A. Khalil
• Keywords: Pyridines; Thiazines; Apoptosis; Antioxidant Response Elements; In Vitro Oocyte Maturation Techniques; Oxidative Stress; 03 medical and health sciences; 0302 clinical medicine; Oocytes; Animals; Cattle; Female; Reactive Oxygen Species

Abstract Increased reactive oxygen species (ROS) generation may disrupt the oocytes function and their competence. In this study, we introduced BTZO‐1, a new supplement that can regulate oxidative stress. Addition of BTZO‐1 during IVM bovine improved developmental competence in term improvement blastocyst rates. addition, quality produced embryos was by decreasing apoptosis level showing decreased number TUNNEL positive cells.