Bronchiectasis in indigenous and non‐indigenous residents of Australia and New Zealand

• DOI: 10.1111/resp.13280
• Publication Date: 2018-03-04T11:12:44Z
• Authors: Sean R. Blackall; Jae B. Hong; Paul King; Conroy Wong; Lloyd Einsiedel; Marc G.W. Rémond; Cindy Woods; Graeme P. Maguire
• Keywords: Adult; Male; Native Hawaiian or Other Pacific Islander; bronchiectasis; Oceania; Pacific Islands; survival analysis; 03 medical and health sciences; 0302 clinical medicine; Risk Factors; Humans; Aged; Proportional Hazards Models; Retrospective Studies; 360; Aged, 80 and over; Australia; Sputum; Middle Aged; 3. Good health; Bronchiectasis; Airway Obstruction; Hospitalization; premature mortality; Female; hospitalization; New Zealand

Bronchiectasis not associated with cystic fibrosis is an increasingly recognized chronic lung disease. In Oceania, indigenous populations experience a disproportionately high burden of We aimed to describe the natural history bronchiectasis and identify risk factors premature mortality within cohort Aboriginal Australians, New Zealand Māori Pacific Islanders, non-indigenous Australians Zealanders.This was retrospective study patients aged >15 years at three hospitals: Alice Springs Hospital Monash Medical Centre in Australia, Middlemore Zealand. Data included demographics, ethnicity, sputum microbiology, radiology, spirometry, hospitalization survival over 5 follow-up.Aboriginal were significantly younger died age than other groups. Age- sex-adjusted all-cause higher for (hazard ratio (HR): 3.9), respiratory-related both (HR: 4.3) Islander people 1.7). Hospitalization common: had 2.9 admissions/person-year 16.9 days hospital/person-year. Despite having poorer prognosis, calculation FACED score suggested milder disease this group. Sputum microbiology varied Aspergillus fumigatus more often isolated from patients. Airflow obstruction common (66.9%) but invariable.Bronchiectasis one It has significant impact on healthcare utilization survival. Differences between are likely relate differing aetiologies understanding drivers disadvantaged will be key.