Effects of high‐impact exercise on the physical properties of bones of ovariectomized rats fed to a high‐protein diet

• DOI: 10.1111/sms.13058
• Publication Date: 2018-01-18T15:31:14Z
• Authors: R. C. Shimano; G. R. Yanagihara; A. P. Macedo; J. S. Yamanaka; A. C. Shimano; J. M. R. S. Tavares; J. P. M. Issa
• Keywords: Osteopontin; Immunostaining

The aim of this study was to evaluate the effects high‐impact physical exercise as a prophylactic and therapeutic means in osteopenic bones rats submitted ovariectomy protein diet intake. A total 64 Wistar were divided into eight groups (n = 8 each), being: OVX , ovx, standard sedentary; OVXE jump; OVXP high‐protein OVXEP SH sham, SHE SHP SHEP jump. surgery consists ovariectomy, sham control surgery. jumping protocol consisted 20 jumps/day, 5 days/week. bone structure evaluated by densitometry, mechanical tests, histomorphometric, immunohistochemical analyses. resulted increased mineral density ( P .049), but decreased maximal load .026) volume fraction .023). benefits demonstrated higher values trained compared sedentary < .001). had immunostaining osteocalcin .004) osteopontin .010) ovx groups. However, .005) jump .017) lower groups, respectively. In experimental model, it concluded that high‐fat can negatively affect tissue not enough suppress deleterious caused ovariectomy.