Typing of Canine Parvovirus Strains Circulating in North-East China

• DOI: 10.1111/tbed.12390
• Publication Date: 2015-07-20T05:01:14Z
• Authors: H. Zhao; J. Wang; Y. Jiang; Y. Cheng; P. Lin; H. Zhu; G. Han; L. Yi; S. Zhang; L. Guo; S. Cheng
• Keywords: Canine parvovirus

Canine parvovirus (CPV) is highly contagious and a major cause of haemorrhagic enteritis myocarditis in dogs. We investigated the genetic variation emerging CPV strains by sequencing 64 VP2 genes from 216 clinical samples dogs Heilongjiang, Jilin, Liaoning, Shandong Hebei 2014. Genetic analysis revealed that CPV-2b was predominant CPV-2a other four provinces. In addition, CPV-2c strain has emerged province. All had Ser-Ala substitution at residue 297 an Ile-Arg 324. Interestingly, five separate canine samples, we found mutation Gln370 to Arg, until now detected only isolates pandas. The phylogenetic showed clear distinctions between epidemic vaccine Chinese countries. Monitoring recent incidence enables evaluation implementation disease control strategies.