Severe acute respiratory syndrome coronavirus 2 and influenza A virus co‐infection alters viral tropism and haematological composition in Syrian hamsters

• DOI: 10.1111/tbed.14601
• Publication Date: 2022-06-01T16:03:34Z
• Authors: Hye Kwon Kim; Jung‐Ah Kang; Kwang‐Soo Lyoo; Tran Bac Le; Yoon Hwan Yeo; Sook‐San Wong; Woonsung Na; Daesub Song; Richard J Webby; Mark Zanin; Dae Gwin Jeong; Sun‐Woo Yoon
• Keywords: Tissue tropism; Pandemic; Coronavirus; Viral Shedding

The ongoing coronavirus disease 2019 (COVID-19) pandemic and its overlap with the influenza season lead to concerns over severe caused by virus acute respiratory syndrome 2 (SARS-CoV-2) co-infections. Using a Syrian hamster co-infection model, SARS-CoV-2 A/California/04/2009 (H1N1), we found (a) more in co-infected animals compared those infected alone but not infection alone; (b) altered hematological changes only animals; (c) tropism tracts of animals. Overall, our study revealed that is associated severity tissue tropism, as well changes, either alone. This article protected copyright. All rights reserved