Successful lung transplantation for chronic Mycobacterium abscessus infection in advanced cystic fibrosis, a case series

• DOI: 10.1111/tid.13046
• Publication Date: 2018-12-31T22:51:18Z
• Authors: Daan Raats; Natalie Lorent; Veroniek Saegeman; Robin Vos; Jakko van Ingen; Geert Verleden; Dirk Van Raemdonck; Lieven Dupont
• Keywords: Mycobacterium abscessus; Lung infection; Pulmonary infection; Nontuberculous Mycobacteria

Abstract Pulmonary Mycobacterium abscessus infection in cystic fibrosis (CF) patients is difficult to treat and considered a contra‐indication for lung transplantation most centers. We present four CF with chronic pulmonary M infection, whom was performed. Through intensive treatment before transplantation, we achieved control of the all but one patient. After mean 16 months follow up, 3 are doing well, without evidence local or disseminated recurrence. One patient died early post‐transplant due an unrelated cause. These findings support possibility favorable outcome infection.