Surgical site infection and risk factors following right lobe living donor liver transplantation in adults: A single‐center prospective cohort study

• DOI: 10.1111/tid.13176
• Publication Date: 2019-09-20T17:44:06Z
• Authors: Aydin Aktas; Cuneyt Kayaalp; Orgun Gunes; Cihan Gokler; Ufuk Uylas; Egemen Cicek; Yasemin Ersoy; Adem Kose; Yasar Bayindir; Cemalettin Aydin; Sezai Yilmaz
• Keywords: Adult; Graft Rejection; Immunosuppression Therapy; Male; Reoperation; Incidence; Age Factors; Antibiotic Prophylaxis; Length of Stay; Middle Aged; Transplant Recipients; Liver Transplantation; 3. Good health; End Stage Liver Disease; 03 medical and health sciences; Treatment Outcome; 0302 clinical medicine; Risk Factors; Living Donors; Humans; Surgical Wound Infection; Female; Prospective Studies

Surgical site infection (SSI) is an important cause of decreased graft survival, prolonged hospital stay, and higher costs following living donor liver transplantation. There are several risk factors for SSI. In this cohort study, we aimed to investigate the incidence SSI at our center associated factors.Adult right lobe transplantations were included in prospective cohort. Patients who died postoperatively within 3 days; patients with infected ascites or open abdomen, cadaveric, pediatric transplants; biologic cryopreserved vascular grafts excluded. Patients' demographic characteristics perioperative surgical findings recorded. follow-up was continued 90 days. CDC-2017 criteria used diagnose presence superficial, deep, organ/space SSI, only organ poorest condition evaluation. The administered similar antibiotic prophylaxes immunosuppressive protocols.A total 101 enrolled which 30 (29.7%) diagnosed Organ/space, superficial noted 90% (27/30), 6.7% (2/30), 3.3% (1/30) patients, respectively. Twenty-five had a remote infection. One more bacteria observed cultures obtained from 28 patients. A donor-recipient age difference >10 years, cold ischemia lasting ≥150 minutes, duration ≥600 intraoperative hemorrhage ≥1000 mL, blood transfusion, biliary leak stricture, mechanical ventilation, intensive care unit infection, need reoperation increased incidence. Preoperative levels glucose, albumin, hemoglobin not found be independent Hospital mortality without SSIs vs 4.4%, P = .61.Organ/space essential part transplantations. Donor-recipient gap, time, complicated surgery, postoperative complications main causes SSIs. Although they did increase mortality, promote rate reoperations, infections, unit, stays.