Association of HIV status with infection by multiple HPV types

• DOI: 10.1111/tmi.13142
• Publication Date: 2018-08-22T16:37:08Z
• Authors: Milena Camargo; Luisa Del Río‐Ospina; Sara Cecilia Soto...; Ricardo Sánchez; Andrea Clemencia ...; Otto Sussmann; Manuel Elkin Pata...; Manuel Alfonso Pa...
• Keywords: 0301 basic medicine; Epidemiology; Life expectancy; Multiple infection; HIV Infections; Comorbidity; Sexual intercourse; Human papillomavirus type 18; 5. Gender equality; Pregnancy; Cd4 lymphocyte count; Human papillomavirus type 58; Risk Factors; Observational study; Hiv infections; Human papillomavirus type 16; Mixed infection; Middle aged; Aged, 80 and over; Infectious disease; Abnormality; Human immunodeficiency virus; Middle Aged; Papanicolaou test; Antiretroviral therapy; Polymerase chain reaction; 3. Good health; Virus dna; Female; Sexuality; Human; Quality of life; Adult; Human papillomavirus; Adolescent; Major clinical study; Papillomavirus infection; Colombia; Pathophysiology; Article; Papillomavirus infections; Young Adult; 03 medical and health sciences; Disease association; Human immunodeficiency virus infection; Humans; Human papillomavirus type 31; Human papillomavirus type 33; Cross-sectional study; Demography; Aged; Womens employment; Papillomavirus Infections; Abortion; Very elderly; Hemoglobin beta chain; Womens health; Disinfection; Young adult; Risk factors; Virus load; Risk factor; Human papillomavirus type 45; Comparative study; Anti human immunodeficiency virus agent; Disease prevalence

Abstract Objectives To identify the clinical and demographic characteristics of HIV ‐positive ‐negative women infected by multiple HPV types. Methods 1399 participated in study (240 1159 women). Samples were provided for Pap tests detection typing PCR . Data collected on infection, frequency type distribution. Odds ratios reported from logistic regression models. Results Compared with women, had higher frequencies cervical abnormality (30% vs 20.8%), prevalence (68.3% 51.3%) more commonly types (78.7% 44.3%). ‐16 was most common detected population, other showing variable associations status. Positive observed between infection status, having than three pregnancies. The odds who used an intrauterine device, a history abortions viral loads >100 000 copies/ml, whilst lower >500 CD 4 cells/mm 3 Conclusions immunosuppression favours high‐risk types, mainly affected low‐grade squamous intraepithelial lesions. Antiretroviral therapy no effect Risk factors related to progressive damage cervix positively associated living