Brown adipose tissue density measured by near-infrared time-resolved spectroscopy in Japanese, across a wide age range

• DOI: 10.1117/1.jbo.23.6.065002
• Publication Date: 2018-06-13T14:19:46Z
• Authors: Sayuri Fuse; Shinsuke Nirengi; Shiho Amagasa; Toshiyuki Homma; Ryotaro Kime; Tasuki Endo; Naoki Sakane; Mami Matsushita; Masayuki Saito; Takeshi Yoneshiro; Yuko Kurosawa; Takafumi Hamaoka
• Keywords: Adult; Aged, 80 and over; Male; 0301 basic medicine; Spectroscopy, Near-Infrared; Anthropometry; Infrared Rays; Middle Aged; Young Adult; 03 medical and health sciences; Adipose Tissue, Brown; Asian People; Japan; Humans; Female; Aged

F18-fluorodeoxyglucose (FDG)–positron emission tomography (PET) along with computed (CT) is a standard method for assessing brown adipose tissue (BAT) activity. We tested the usefulness of near-infrared time-resolved spectroscopy (NIRTRS) as simple and noninvasive evaluating BAT density (BAT-d) by examining effects some factors known to influence The total hemoglobin concentration parameter BAT-d was evaluated using NIRTRS in supraclavicular region 413 Japanese individuals. associations were analyzed between sex, age, percentages body fat (%BF), visceral (VF), seasonal ambient temperature (AmT) fluctuations. Age associated decreased (P < 0.05). There no sex difference BAT-d, except those their twenties. Multivariate analyses revealed that %BF VF correlated lower AmT (around 4°C or 5°C) 4 6 weeks prior measurement day an increase BAT-d. Our results analogous reported FDG18-PET / CT, indicating NIRTRS. might during after decreases than 5°C.