A dosimetry study precisely outlining the heart substructure of left breast cancer patients using intensity‐modulated radiation therapy

• DOI: 10.1120/jacmp.v15i5.4624
• Publication Date: 2017-02-27T23:39:09Z
• Authors: Ling‐li Fan; Yang‐kun Luo; Jing‐hui Xu; Ling He; Jie Wang; Xiao‐bo Du
• Keywords: Supine position; Left breast

The purpose of this study was to evaluate the feasibility delineating substructure heart by using 64‐slice spiral CT coronary angiography (CTA) in breast cancer patients who underwent left breast‐conserving surgery, and compare dosimetric differences between targets organs at risk prone supine positions intensity‐modulated radiation therapy (IMRT) planning. From January December 2011, ten surgery were enrolled study. CTA performed both during simulation, conventional scanning without same time. Image registration for paired image series a commercially available planning system. In series, clinical target volume (CTV) whole breast, (PTV), bilateral lungs (L‐Lung, R‐Lung), spinal cord, contralateral (R‐Breast), delineated. ventricular (LV) anterior descending arteries (LAD) (LAD‐PRV) LAD (LAD with 1 cm margin) outlined. For each patient, two separate IMRT plans developed positions. A total 20 generated. following indicators compared: Dmean D95 PTV; Dmean, V5, V20 lung; V10, V20, V25, V30, V40 its substructures (LAD‐PRV, LV); V5 right Dmax breast. Using delineate is simple straightforward. Plans reached prescribed dose PTV significant differences. Dose distributions acceptable However, LAD‐PRV, LV, heart, L‐Lung received smaller doses position than plans. values reduced , L‐Lung. addition, V25 lessened LV while decreased L‐Lung, respectively. Similarly, V10 V30 28.31% ( ) cut back most Asian women average‐sized breasts after conserving treatment (BCT), positioning will reduce ipsilateral lung, which may incidence cardiovascular events radiotherapy more position. easy intuitive. It cost‐effective highly recommended IMRT. dose‐volume limits remain be determined. PACS number: 87.55.dk