Serine one-carbon catabolism with formate overflow

• DOI: 10.1126/sciadv.1601273
• Publication Date: 2016-10-29T01:44:33Z
• Authors: Johannes Meiser; Sergey Tumanov; Oliver Maddocks; Christiaan Fred L...; Dimitris Athineos; Niels Van Den Broek; Gillian M. Mackay; Eyal Gottlieb; Karen Blyth; Karen Vousden; Jurre J. Kamphorst; Alexei Vazquez
• Keywords: Catabolism; Purine metabolism

Serine catabolism results in formate efflux that exceeds anabolic demands for purine synthesis.