A minimal RNA ligand for potent RIG-I activation in living mice

• DOI: 10.1126/sciadv.1701854
• Publication Date: 2018-02-22T01:50:27Z
• Authors: Melissa M. Linehan; Thayne H. Dickey; Emanuela S. Molinari; Megan E. Fitzgerald; Olga Potapova; Akiko Iwasaki; Anna M. Pyle
• Keywords: RIG-I

Short stem-loop RNAs activate RIG-I in mice, activating the innate immune system via specific patterns of gene expression.