cAMP metabolism controls caspase-11 inflammasome activation and pyroptosis in sepsis

• DOI: 10.1126/sciadv.aav5562
• Publication Date: 2019-05-22T23:16:19Z
• Authors: Ruochan Chen; Ling Zeng; Shan Zhu; Jiao Liu; Herbert J. Zeh; Guido Kroemer; Haichao Wang; Timothy R. Billiar; Jianxin Jiang; Daolin Tang; Rui Kang
• Keywords: Pyroptosis

Targeting immunometabolism is a strategy to prevent infection-mediated septic death.