Functionally distinct resident macrophage subsets differentially shape responses to infection in the bladder

• DOI: 10.1126/sciadv.abc5739
• Publication Date: 2020-11-26T00:16:47Z
• Authors: Livia Lacerda Mar...; Matthieu Rousseau; Hugo Varet; Rachel Legendre; Rebecca Gentek; Javier Saenz Coro...; Marc Bajenoff; Elisa Gomez Perdi...; Molly A. Ingersoll
• Keywords: 0301 basic medicine; 0303 health sciences; [SDV.IMM] Life Sciences [q-bio]/Immunology; [SDV]Life Sciences [q-bio]; Gene Expression Profiling; Macrophages; Urinary Bladder; 3. Good health; [SDV] Life Sciences [q-bio]; Mice; 03 medical and health sciences; [SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN]; Urinary Tract Infections; [SDV.IMM]Life Sciences [q-bio]/Immunology; [SDV.BBM.GTP] Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN]; Animals; Research Articles

Phenotypically and spatially distinct macrophage subsets reside in the bladder with differing roles in response to infection.