Xenogeneic skin transplantation promotes angiogenesis and tissue regeneration through activated Trem2 + macrophages

• DOI: 10.1126/sciadv.abi4528
• Publication Date: 2021-12-01T18:55:43Z
• Authors: Dominic Henn; Kellen Chen; Tobias Fehlmann; Artem A. Trotsyuk; Dharshan Sivaraj; Zeshaan N. Maan; Clark A. Bonham; Janos A. Barrera; Chyna J. Mays; Autumn H. Greco; Sylvia E. Moortga...; John Qian Lin; Sydney R. Steele; Deshka S. Foster; Jagannath Padmana...; Arash Momeni; Dung Nguyen; Derrick C. Wan; Ulrich Kneser; Michael Januszyk; Andreas Keller; Michael T. Longaker; Geoffrey C. Gurtner
• Keywords: TREM2

Vitamin D–activated Trem2 + macrophages provide a novel strategy to develop advanced cell therapies for complex wounds.