A First-Generation Haplotype Map of Maize

• DOI: 10.1126/science.1177837
• Publication Date: 2009-11-20T07:59:08Z
• Authors: Michael A. Gore; Jer-Ming Chia; Robert J. Elshire; Qi Sun; Elhan S. Ersoz; Bonnie L. Hurwitz; Jason A. Peiffer; Michael D. McMullen; George S. Grills; Jeffrey Ross-Ibarra; Doreen H. Ware; Edward S. Buckler
• Keywords: Recombination, Genetic; 0301 basic medicine; 2. Zero hunger; Heterozygote; Chromosome Mapping; Genetic Variation; Sequence Analysis, DNA; Breeding; Polymorphism, Single Nucleotide; Zea mays; Chromosomes, Plant; Evolution, Molecular; 03 medical and health sciences; Haplotypes; Hybrid Vigor; Selection, Genetic; Genome, Plant; Sorghum; Genome-Wide Association Study

Maize is an important crop species of high genetic diversity. We identified and genotyped several million sequence polymorphisms among 27 diverse maize inbred lines discovered that the genome was characterized by highly divergent haplotypes showed 10- to 30-fold variation in recombination rates. Most chromosomes have pericentromeric regions with suppressed appear influenced effectiveness selection during development may be a major component heterosis. found hundreds selective sweeps differentiated probably contain loci are key geographic adaptation. This survey diversity provides foundation for uniting breeding efforts across world dissecting complex traits through genome-wide association studies.