Alterations of myc , myb , and ras Ha Proto-Oncogenes In Cancers Are Frequent and Show Clinical Correlation

• DOI: 10.1126/science.3941898
• Publication Date: 2006-10-05T20:28:52Z
• Authors: Jun Yokota; Yasuko Tsunetsugu...; Hector Battifora; Carol Le Fevre; Martin J. Cline
• Keywords: MYB

Alterations of c-myc, c-rasHa, or c-myb oncogenes were found in more than one-third human solid tumors. Amplification c-myc occurred advanced, widespread tumors aggressive primary Apparent allelic deletions c-rasHa and can be correlated with progression metastasis carcinomas sarcomas.