Aging Fly Cell Atlas identifies exhaustive aging features at cellular resolution

• DOI: 10.1126/science.adg0934
• Publication Date: 2023-06-15T13:59:07Z
• Authors: Tzu-Chiao Lu; Maria Brbić; Ye-Jin Park; Tyler Jackson; Jiaye Chen; Sai Saroja Kolluru; Yanyan Qi; Nadja Sandra Kath...; Xiaoyu Tracy Cai; Seungjae Lee; Yen-Chung Chen; Niccole Auld; Chung-Yi Liang; Sophia H. Ding; Doug Welsch; Samuel D’Souza; Angela Oliveira P...; Robert C. Jones; Jure Leskovec; Eric C. Lai; Hugo J. Bellen; Liqun Luo; Heinrich Jasper; Stephen R. Quake; Hongjie Li
• Keywords: Model Organism; On the fly; Cell type

Aging is characterized by a decline in tissue function, but the underlying changes at cellular resolution across organism remain unclear. Here, we present Fly Cell Atlas, single-nucleus transcriptomic map of whole aging