Chronic antigen in solid tumors drives a distinct program of T cell residence

• DOI: 10.1126/sciimmunol.add5976
• Publication Date: 2023-06-02T17:58:24Z
• Authors: Noah V. Gavil; Milcah C. Scott; Eyob Weyu; Olivia C. Smith; Stephen D. O’Flan...; Sathi Wijeyesinghe; Sahar Lotfi-Emran; Stephen L. Shiao; Vaiva Vezys; David Masopust
• Keywords: Mice; Neoplasms; Tumor Microenvironment; Animals; CD8-Positive T-Lymphocytes; Antigens; Prognosis; Immunologic Memory; 3. Good health

Analyses of healthy tissue reveal signatures that identify resident memory CD8