Inferring Signaling Pathway Topologies from Multiple Perturbation Measurements of Specific Biochemical Species

• DOI: 10.1126/scisignal.2000517
• Publication Date: 2010-03-16T22:03:53Z
• Authors: Tian-Rui Xu; Vladislav Vyshemi...; Amélie Gormand; Alex von Kriegsheim; Mark Girolami; George S. Baillie; Dominic Ketley; Allan J. Dunlop; Graeme Milligan; Miles D. Houslay; Walter Kolch
• Keywords: Signaling proteins

Bayesian inference–based modeling identifies the most likely paths through a signaling network.