TGF-β receptor I/II trafficking and signaling at primary cilia are inhibited by ceramide to attenuate cell migration and tumor metastasis

• DOI: 10.1126/scisignal.aam7464
• Publication Date: 2017-10-24T18:30:34Z
• Authors: Salih Gencer; Natalia Oleinik; Jisun Kim; Shanmugam Panneer...; Ryan De Palma; Mohammed Dany; Rose Nganga; Raquela J. Thomas; Can E. Senkal; Philip H. Howe; Besim Ogretmen
• Keywords: Primary (astronomy)

Ceramide forms complexes with Smad7 to inhibit cell migration–associated TGF-β–sonic hedgehog signaling in primary cilia.