The scaffolding protein Cnk binds to the receptor tyrosine kinase Alk to promote visceral founder cell specification in Drosophila

• DOI: 10.1126/scisignal.aan0804
• Publication Date: 2017-10-24T18:30:34Z
• Authors: Georg Wolfstetter; Kathrin Pfeifer; Jesper R. van Dijk; Fredrik Hugosson; Xiangyi Lu; Ruth H. Palmer
• Keywords: 0301 basic medicine; Zygote; Receptor Protein-Tyrosine Kinases; Cell Differentiation; Mesoderm; 03 medical and health sciences; Drosophila melanogaster; Animals; Drosophila Proteins; Humans; Anaplastic Lymphoma Kinase; Databases, Nucleic Acid; Protein Kinases; Adaptor Proteins, Signal Transducing; Sequence Deletion

Alk signaling in the developing Drosophila visceral mesoderm requires the scaffolding protein Cnk and its binding partner Ave.