ORAI1, STIM1/2, and RYR1 shape subsecond Ca 2+ microdomains upon T cell activation

• DOI: 10.1126/scisignal.aat0358
• Publication Date: 2018-12-19T00:19:17Z
• Authors: Björn-Philipp Die...; René Werner; Paula Weidemüller; Frederik Czarniak; Lola Hernandez; Cari Lehmann; Annette Rosche; Aileen Krüger; Ulrike Kaufmann; Martin Vaeth; Antonio V. Failla; Bernd Zobiak; Farid I. Kandil; Daniel Schetelig; Alexandra Ruthenbeck; Chris Meier; Dmitri Lodygin; Alexander Flügel; Dejian Ren; Insa M. A. Wolf; Stefan Feske; Andreas H. Guse
• Keywords: Orai1; Lipid microdomain

The proteins that generate Ca 2+ signals within the first second after T cell activation are identified.