Essential requirement for JPT2 in NAADP-evoked Ca 2+ signaling

• DOI: 10.1126/scisignal.abd5605
• Publication Date: 2021-03-23T19:15:10Z
• Authors: Gihan S. Gunaratne; Eugen Brailoiu; Shijun He; Ellen M. Unterwald; Sandip Patel; James T. Slama; Timothy F. Walseth; Jonathan S. Marchant
• Keywords: 0301 basic medicine; SARS-CoV-2; COVID-19; Affinity Labels; Virus Internalization; Second Messenger Systems; Recombinant Proteins; 3. Good health; 03 medical and health sciences; HEK293 Cells; Gene Knockdown Techniques; Animals; Humans; Click Chemistry; Calcium Channels; Calcium Signaling; Carrier Proteins; Transcriptome; Microtubule-Associated Proteins; NADP

A protein that enables the activation of two-pore channels by NAADP is identified.