mTORC2 controls the activity of PKC and Akt by phosphorylating a conserved TOR interaction motif

• DOI: 10.1126/scisignal.abe4509
• Publication Date: 2021-04-13T19:15:54Z
• Authors: Timothy R. Baffi; Gema Lordén; Jacob M. Wozniak; Andreas Feichtner; Wayland Yeung; Alexandr P. Kornev; Charles C. King; Jason C. Del Rio; Ameya J. Limaye; Julius Bogomolovas; Christine M. Gould; Ju Chen; Eileen J. Kennedy; Natarajan Kannan; David J. Gonzalez; Eduard Stefan; Susan S. Taylor; Alexandra C. Newton
• Keywords: Motif (music); mTORC2; Conserved sequence

Phosphorylation of an evolutionarily conserved motif by mTORC2 enables the maturation AGC kinases.