Restoration of Norepinephrine-Modulated Contextual Memory in a Mouse Model of Down Syndrome

• DOI: 10.1126/scitranslmed.3000258
• Publication Date: 2009-11-19T06:54:44Z
• Authors: A. Salehi; M. Faizi; D. Colas; J. Valletta; J. Laguna; R. Takimoto-Kimura; A. Kleschevnikov; S. L. Wagner; P. Aisen; M. Shamloo; W. C. Mobley
• Keywords: Locus coeruleus

Cognitive deficits in mice with a Down syndrome–like genetic defect can be reversed precursors to the neurotransmitter norepinephrine.