Androgen Receptor Promotes Hepatitis B Virus–Induced Hepatocarcinogenesis Through Modulation of Hepatitis B Virus RNA Transcription

• DOI: 10.1126/scitranslmed.3001143
• Publication Date: 2010-05-19T21:53:37Z
• Authors: Ming-Heng Wu; Wen-Lung Ma; Cheng-Lung Hsu; Yuh-Ling Chen; Jing-Hsiung James Ou; Charlotte Kathryn...; Yao-Ching Hung; Shuyuan Yeh; Chawnshang Chang
• Keywords: Male; Mice, Knockout; 0301 basic medicine; Hepatitis B virus; Carcinoma, Hepatocellular; Curcumin; Base Sequence; Liver Neoplasms; Antineoplastic Agents; Mice, Transgenic; Hep G2 Cells; Cell Transformation, Viral; Hepatitis B; 3. Good health; Gene Expression Regulation, Neoplastic; Disease Models, Animal; Mice; 03 medical and health sciences; Liver; Androgen Receptor Antagonists; Animals; Humans; Diethylnitrosamine

Targeting androgen receptor may prevent hepatitis B virus–induced liver cancer.