The Effect of Treatment Expectation on Drug Efficacy: Imaging the Analgesic Benefit of the Opioid Remifentanil

• DOI: 10.1126/scitranslmed.3001244
• Publication Date: 2011-02-16T22:31:12Z
• Authors: Ulrike Bingel; Vishvarani Waniga...; Katja Wiech; Roisin Ni Mhuirch...; Michael C. Lee; Markus Ploner; Irene Tracey
• Keywords: Adult; Male; Brain; Pain; Magnetic Resonance Imaging; 3. Good health; Analgesics, Opioid; Remifentanil; Young Adult; 03 medical and health sciences; 0302 clinical medicine; Piperidines; Humans; Female

An individual’s expectation that a pain treatment will or will not work can alter both its subjective effectiveness and the pain-related activity in the brain.